Pretargeted radioimmunotherapy in rapidly progressing, metastatic, medullary thyroid cancer
نویسندگان
چکیده
منابع مشابه
Pretargeted radioimmunotherapy in the treatment of metastatic medullary thyroid cancer
Medullary thyroid carcinoma (mtc) is a rare cancer (less than 8% of all thyroid cancers) that occurs both as a familial and as a sporadic disease. Total thyroidectomy with dissection of the ipsilateral and central lymph nodes, sometimes extended to contralateral dissection, is the primary treatment of hereditary and sporadic mtc alike. after surgery, many patients are cured, especially those wi...
متن کاملEnhanced antitumor activity of combined pretargeted radioimmunotherapy and paclitaxel in medullary thyroid cancer xenograft.
A significant antitumor effect associated with moderate toxicity was obtained previously with anticarcinoembryonic antigen x antidiethylene-triaminepentaacetic acid (DTPA)-indium F6-734 bispecific antibody and iodine-131-labeled DTPA-indium bivalent hapten in an animal model of medullary thyroid cancer (MTC). The purpose of this study was to determine whether the cytotoxic agents doxorubicin an...
متن کاملImaging Techniques for Metastatic Thyroid Medullary Cancer
Medullary thyroid carcinoma (MTC) originating from the calcitoninsecreting parafollicular cells is a relatively uncommon disease. It constitutes 3% to 10% of all thyroid malignancies (1). MTC may occur in sporadic or rarely familial form as a part of multiple endocrine neoplasia syndrome type 2A and 2B. The sporadic MTC is mostly detected on the basis of clinical symptoms. Calcitonin that is se...
متن کاملMedullary Thyroid Cancer: A Review
Thyroid cancer is a malignancy of the thyroid parenchymal cells. There are four main types of thyroid cancer: papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), anaplastic thyroid carcinoma (ATC), and Medullary thyroid carcinoma (MTC). Medullary thyroid cancer (MTC) is a rare neuroendocrine tumor of the thyroid gland derived from parafollicular C-cells that produce calcitonin (CT...
متن کامل2012 European thyroid association guidelines for metastatic medullary thyroid cancer.
Distant metastases are the main cause of death in patients with medullary thyroid cancer (MTC). These 21 recommendations focus on MTC patients with distant metastases and a detailed follow-up protocol of patients with biochemical or imaging evidence of disease, selection criteria for treatment, and treatment modalities, including local and systemic treatments based on the results of recent tria...
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ژورنال
عنوان ژورنال: Cancer
سال: 2010
ISSN: 0008-543X
DOI: 10.1002/cncr.24800